Alexander eventually fell in love with the surgeon, and in 2014, he proposed to her, and they started planning a lavish wedding for the following year. (The patient who survived had the implant removed.). Paolo Macchiarini traveled to Illinois to operate on toddler Hannah Warren, who was born without a trachea in 2013. The couple had traveled extensively, but there were a It won Dr. Macchiarini international news coverage and cemented his place as a celebrity scientist. A 29-year old woman from New Brunswick, New Jersey, posed as a high school student and attended classes for four days before she was caught and arrested. Abu Dhabi Paolo Macchiarini Every patient had another, nonlethal option, Pierre Delaere, a trachea expert at KU Leuven and an early critic of Macchiarini, said in an email to Science. After realizing other treatment methods wouldnt help, he concluded that Ms. Sein had a logical, thoughtful grasp of transplantations risks and of her health condition. He is still licensed to practice medicine in Europe. No one wanted to collaborate with me. Benita fell for Macchiarini while a producer for NBC, working on a story on him in 2013. Surgeon Paolo Macchiarini was hailed for turning the dream of regenerative medicine into a reality until he was exposed as a con artist and false prophet. California They recently published an article in the New England Journal of Medicine admitting that stem cell research has mostly failed to live up to its therapeutic promise. He was one of the best con men I have ever come across. In September 2020, Swedish prosecutors announced charges against him for aggravated assault in connection to three surgeries that he had performed at the. And then there are the surgeons on Dr. Death. The charismatic Italian surgeon who designed it foresaw a future where hearts and lungs could be made from plastic, and organ donations became a thing of the past. "If I made a checklist of what I wanted a man to be, he had everything.". An independent investigator agreed. WebPaolo Macchiarini (born 22 August 1958): 2 is a Swiss-born Italian thoracic surgeon and former regenerative medicine researcher who became known for research fraud and The fact that he could keep all the details straight and compartmentalize these different lives and lies is really amazing.. Who Were Paolo Macchiarinis Victims? - The Cinemaholic I didnt want Paolo to not be the man I believed him to be, she told Vanity Fair. In late 2014, four doctors in Sweden accused him of fraud, saying that he'd falsified data in six of the papers he had published. On May 13, Alexander left her job. Thats what our experience of medical research leads us to suspect. 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That meant the donor trachea was accompanied by a blood supply that Dr. Genden connected to Ms. Seins blood vessels. Singapore The court had to apply the intentional indifference standard for the assault charges, he says, which is difficult to prove. Macchiarini gave his regenerating windpipes to 17 or more patients worldwide. Dressed in a white lab coat or in surgical scrubs, with his broad, handsome face and easy charm, he certainly looked the part. Delaere was one of the earliest and harshest critics of Macchiarinis engineered airways. What's next for abortion rights in America? There Was Nothing Anybody Could Do for These Patients. Now There Is. Fill in your details below or click an icon to log in: You are commenting using your WordPress.com account. Its like when you get on a rocket ship., At times, he felt in a dreamlike state, he said. You cant justify doing experimental surgery and immunosuppression when you see something else that looks perfect, so you realize, wow, were out of business., As Dr. Macchiarinis work drew criticism, Dr. Genden revived his idea, but was uncertain about trying it. Its a problematic idea with unfortunate side effects. Recently, Ms. Sein, covering the hole with her hand to speak, enthused about having the energy to cook sesame chicken for the first time and how she aims to visit relatives in Puerto Rico. Nearly all of those patients have died. If the sins of Karolinska have been committed elsewhere, it is partly because medical research facilities share a common milieu, which harbours common dangers. The trachea has been characterized as a simple tube, but its very complex, Dr. Delaere said. Likewise the whole idea of a wedding: Macchiarini was still married to his wife of 30 years. KI officials let him do this. They didnt even seek the approval of Stockholms ethical review board, which is based at Karolinska. Delaeres damning criticisms appeared in major medical journals, including the Lancet, but werent taken seriously by Karolinskas leadership. For their efforts, the whistleblowers were punished. He was born in Basel, Switzerland to Italian parents. The popular press also has a lot to answer for. Macchiarinis deceit was so outlandish, Vanity Fair sought the opinion of the Harvard professor Ronald Schouten, an expert on psychopaths, who gave this diagnosis-at-a-distance: Macchiarini is the extreme form of a con man. I didnt want the fairy tale to end., Alexander also hired a private investigator, a former Pennsylvania State Police detective named Frank Murphy. Each new scientific discovery brings a flood of stories about how it will revolutionise medicine one day soon. Louisiana Woman Disappeared After Giving Somebody A Ride, 5 Things That Still Bother Us About The Unsolved Maura Murray Case, Two Texas Teens Left After Curfew In 1988 And Never Returned, What Happened To Zion Foster? WebIn reality, Paolo had not worked with the Pope, and he was still married to his wife of 30 years. All rights reserved. There is South Koreas Hwang Woo-suk who, in 2004, falsely claimed to have created the first human embryonic stem cells by means of cloning. Ive never in my experience witnessed a fraud like this, with this level of international flair, Murphy told Vanity Fair. If she talked for over five minutes, she had to stop because I couldnt breathe.. I have to expose him.". Macchiarini has consistently claimed he is innocent. But for now, lets focus solely on his medical patients, shall we? Paolo Macchiarinis most notable patient is Claudia Castillo. Born in 1977, this Colombian living in Spain woman suffered from tuberculosis-damaged airways. As for Keziah Shorten, who suffered from trachea cancer, Paolo Macchiarini did a transplant on her on July 13, 2010, which failed the very next year. But as the big day approached, Alexander saw these plans unravel, and finally realised that her lover had lied about almost everything. Most protagonists on medical dramas are modern-day heroes. By this year, Dr. Genden said, her condition had deteriorated so that if we delay further, its not going to work out.. They also cited a loophole known as compassionate use. (LogOut/ By using a patients own cells, Dr. Macchiarini sought to rectify an age-old problem with transplants involving donated organs, which the body sometimes rejects as foreign tissue. In place of clinical data, there are gushing testimonials. Emanuela Pecchia: Everything We Know On Paolo Macchiarini Wife The donor was a young man (identifying details are being withheld to protect privacy). In other countries, more of Macchiarinis patients died after receiving one of his artificial windpipes. In the months and years following their respective surgeries, all of them except Dmitri Onogda have passed away due to post-operative complications. None other than Pope Francis would officiate, and his papal palace in Castel Gandolfo would serve as the venue. When you implant a synthetic trachea you have one certainty, and that is that the patient will die as a result of it, Delaere says in the email. She became close to Paolo as she opened her heart to him about how hard it was for her daughter, then nine years old, to lose her father. Learn how your comment data is processed. Japan Any woman would swoon for such a catch! How did the GameStop stock spike on Wall Street happen? "I have to tell people. Born in 1977, this Colombian living in Spain woman suffered from tuberculosis-damaged airways. Tokyo Las Vegas Benita Alexander wearing a wig as she tracked down Paolo in Barcelona [Investigation Discovery]. Nor did they impress the institutes ethics council when Delaere lodged a formal complaint. Its kind of a marginal substitute, and many patients need further interventions to maintain their airways.. Last year, however, the dream soured, exposing an ugly reality. In 2015, the Karolinska Institute hired an independent investigator named Dr. Bengt Gerdin to look into the Macchiarini situation, per the Times. There was another woman from the Czech Republic with mucoepidermoid carcinoma who received such a transplant. As per In 2018, KI finally released the findings of its second investigation, which confirmed he had committed misconduct. You can see this in the speed with which his breakthroughs were accepted. In fact, the surgeon was still married to his wife of nearly 30 years. Virginia I could feel it in my lungs.. But some of Alexander's friends began to become suspicious. Plus: NYC sixth-grader struck and killed by stray bullet; New Hampshire police search for person of interest in double homicide; Fyre Festival fraudster released early from prison; and manhunt continues for escaped Texas prisoner. Her global quest to find out the truth about the man who left her personal and professional life in shambles is documented in He Lied About Everything on Investigation Discovery. Border crisis: Whats happening at the US-Mexico border? And in 2014, four Karolinska University Hospital doctors filed two separate reports claiming that Macchiarinis scientific papers described exaggerated the positive results of the operations and incorrectly describe[d] the postoperative status of the patients and the functionality of the implant, the timeline says. Dr. Paolo Macchiarini at the Karolinska Institute in Stockholm in 2013. All but one died following severe complications with the implants. Back in New York, Benita found herself unable to stop thinking about Paolo's patients. But in October 2017, the attorney general's office announced that a crime could not be proven, because the patients might have died anyway. They and their loved ones fall victim to false hope. However, behind closed doors, Dr. Macchiarini was hiding a secret the procedures were not working. Emanuela Pecchia [Paolo Macchiarini Wife] Biography, Her transformation follows a groundbreaking experimental procedure she underwent in January: the first time, medical experts believe, a donor trachea has been successfully directly transplanted into another person. No one is more powerless than a patient with a disease, said Dr. Gerdin. China On Friday Mr. Hurtig declined to comment on Paolos private affairs.. His lawyer did not respond to emails from Science today. By 2011, he was working in Sweden at one of the worlds most prestigious medical universities, the Karolinska Institute, whose professors annually select the winner of the Nobel prize in physiology or medicine. There was nothing anybody could do for these patients, said Dr. Genden, who became captivated by the problem in medical school 30 years ago after a patient with a tracheal tumor died. As a subscriber, you have 10 gift articles to give each month. From Confines Of Russia, Controversial Stem-Cell Surgeon They identified many problems with the way the twin organisations handled him. Emanuela Pecchia: Everything We Know Euan Ward reported from London, and Christina Anderson from Bastad, Sweden. He performed a synthetic trachea transplant on, In 2013, he met documentary television producer. The story portrayed Macchiarini, who was already married at the time, as a serial fabulist who exaggerated or lied about degrees, academic appointments, and Illinois In this episode, eyewitnesses, officials, and some of Paolos victims thus reveal how they got conned by him, with his former lover television producer Benita Alexander at the front and center. 2023 American Association for the Advancement of Science. They reopened the case in 2020, this time charging Macchiarini on lesser counts of aggravated assault and severe bodily harm. Please try again later. The very next day, she got an email from a friend that outlined the Pope's plans to visit South America on Benita and Paolo's wedding day. The couple has been married for 30 years now. Benita Alexander and Paolo Macchiarini [Investigation Discovery]. Get more great content like this delivered right to you! There are also plenty of desperate patients who believe because theyve been told countless times that stem cells are the cure, and who cannot wait any longer for mainstream medicine. KI fired Macchiarini in March 2016, 2 months after the Swedish documentary came out. Benita was also growing increasingly concerned, because she had not yet been introduced to Paolo's children or even seen where she was meant to live with him in Barcelona. TikToker Says Her Celebrity Surgeon Ex Conned Her Out of $50K According to the Times, Macchiarini seen below in a 2017 interview on Swedens TV4 Nyheterna performed 20 tracheal regeneration procedures across Europe and in the United States but hid the fact that the transplants were failing. Support for Macchiarini remained strong, even as his patients began to die. Macchiarini, who denied the charges against him, wasnt directly accused of killing any of the three patients. Why dont the Electoral College and popular vote always match up? "Maybe it happened because I am a journalist, and once I sort of woke up and put my journalist hat back on, I could expose him," she said. According to the judgment in Macchiarinis case, hospital staff said that Cetir had around 40 near-death experiences and was conscious but unable to breathe for many of them. However, he eventually found out about his previous associations. BRAVE Combat Federation Countless news stories declared it a medical breakthrough. They exchange their vows in Italy. She had already spent $10,000 on engraved invitations made for a guest list that included the Obamas, the Clintons, Vladimir Putin, and Elton John. That drama began about a decade ago when Dr. Paolo Macchiarini, working at Swedens famed Karolinska Institute, garnered headlines and accolades for replacing Benita traveled to Paolo's Barcelona home with two friends and a video camera. The media began calling him "Dr. Frankenstein" and said that he committed "the world's biggest medical fraud.". This went on for three years until, just recently, Grinnemo was cleared of all wrongdoing. Likewise, they didnt undertake a proper risk assessment of the procedure, nor did Macchiarinis team seek government permits for the plastic windpipes, stem cells, and chemical growth factors they used. For Ms. Sein, the procedure was a long-sought dream. It did much the same for Macchiarinis windpipe replacements. About 11 centimeters (4 inches) long, one side curves like a halfpipe, composed of cartilage rings and ligaments. Macchiarini was also charged with but acquitted of assault charges related to the deaths of two more of his artificial windpipe patients, an Eritrean man named Andemariam Beyene and an American man named Christopher Lyles, according to BBC News. At any rate, some of his most powerful friends were themselves Nobel judges until, with his fall from grace, they fell too. I thought, If they do a transplant for everything, they should do a transplant for trachea, she recalled. A High-Flying Italian Surgeons Fall From Grace, https://www.nytimes.com/2022/06/17/world/europe/macchiarini-windpipe-surgeon-deaths.html. The first was a Vanity Fair article about his affair with Benita Alexander, an award-winning producer for NBC News. The district court in Solna today found Paolo Macchiarini not guilty on other charges, including aggravated assault, relating to three patients he treated while working for the famed Karolinska Institute (KI). Its actually meaningless for him, Gerdin says. The idea is that scientific progress is driven by the genius of a few. Paolo Macchiarinis most notable patient is Claudia Castillo. But, we now know that the success of this operation was a lie, and the complications she suffered because of it were kept under wraps for a really long time. She has since had the synthetic trachea removed. Benita Alexander and Paolo Macchiarini in Venice, Italy [Investigation Discovery]. Macchiarini was turning the dream of regenerative medicine into a reality. In 2011, Dr. Macchiarini, a renowned leader in the field of regenerative medicine, took the medical world by storm when he built and implanted the worlds first bioartificial windpipe. She says it may mean the judges thought he and the patients believed time was short and options were few. Sorry we couldn't set a reminder for you this time. Dr. Genden said some scientists told him Youre out of your mind because trying a transplant would risk his reputation. When the blood vessels were finally connected, the donor trachea began bleeding.
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