There is no single factor that can explain this difference. Choi J, et al. Tumors of the bile ducts, gallbladder and ampulla. For any product made after August 2018, the Prop 65 labels typically say something like this: WARNING: This product can expose you to [name of chemical], which is known to the State of California to cause cancer. 2018; doi:10.1016/S1470-2045(18)30188-8. Paragraph four of my prior post should read: Like elk or deer, 100% pastured, grass fed, never-fed-grain beef bears little resemblance to factory beef.. They inject dye and take an X-ray of the area. The American Cancer Society medical and editorial content team. No, Caillou does not have cancer. . information is beneficial, we may combine your email and website usage information with Contact the department that sent the bill if theres a difference between your bill and the Explanation of Benefits. For some people, treatment can destroy the cancer. Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Pete Wilson has proposed increasing that by $6.5 million in the next budget. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Nobody is attacking state funding for breast cancer or AIDS programs. Andre T, et al. Porridge, wheat dumplings, and beignets are some of Nigers popular snacks.[3]. Bile duct cancer forms inside your bile duct, a thin tube that moves a fluid called bile to your small intestine. This uses a tool called an endoscope thats like a camera on the end of a cable. Colorectal cancer: Screening and management (adult). To stay safe, protect your skin with sunscreen, wear a hat and sunglasses, and avoid tanning salons. This governor, who normally sides with the private sector, said he rejected the bill because it designated a private, nonprofit foundation as the program administrator. But it's not clear what dose and what length of time would be needed to reduce the risk of colon cancer. You can help reduce your risk of cancer by making healthy choices like eating right, staying active and not smoking. Weve invested more than $5 billion in cancer research since 1946, all to find more and better treatments, uncover factors that may cause cancer, and improve cancer patients quality of life. This is largely due to the production of telomerase, which protects the telomeres from free radical damage. Related Articles. It may be a substance in the air, a product you use, or a chemical in foods and drinks. Talk with the team social worker about sources of short-term help. Standardization is necessary when comparing populations that differ in respects to age because otherwise countries with older populations would have vastly higher rates of cancer. Factory beef is forced to eat this unhealthy grain diet on the feed lot to fatten it up. Lip cancer is a type of oral cancer that begins in the mucosa of the mouth. Little Bill is based on Bill Cosby's son, Ennis William Cosby, and was voiced by Xavier Pritchett. Mayo Clinic. All of this makes it easier to capture and track than a disease like prostate cancer, which might not come to clinical attention for a long time, if ever. The tough, tiny fibers in asbestos help strengthen products like roof shingles, ceiling tiles, and car parts. Mayo Clinic Minute: Who should be screened for colorectal cancer? Experts know this from looking at data from over 1.2 million people across the U.S. You can't avoid pollution, but you can do your part to avoid contributing to it by walking or biking instead of driving. Bile duct stones. Your doctor inserts a needle through your skin and into a bile duct in your liver. The upside-down food pyramid diet guidelines have closely correlated to the exploding chronic disease rates in this country. These statistics are age-standardized a summary measure of the rate of disease that a population would have if it had a standard age structure. We can do no less for our men than we do for our women.. Randy, Very astute point re: grains & chronic inflammation. Toll-free Number: 1-866-470-6242 health information, we will treat all of that information as protected health But just putting the similarities to assess the rising situation of Blood Cancer, i have also doubts that some type of controlled radiation instrument can create blood cancer, or some medicine good for one disease can generate other disease blood cancer. 2022; doi:10.1200/JCO.21.02505. . Whether you want to learn about treatment options, get advice on coping with side effects, or have questions about health insurance, were here to help. Its also important to follow recommended screening guidelines, which can help detect certain cancers early. You show incredibly bad third world nations in Africa where people die daily from malnutrition as having the lowest cancer rates and we are to use that information as if it is of some importance? In general, colon cancer begins when healthy cells in the colon develop changes (mutations) in their DNA. Sometimes during a serious illness, people find it hard to pay their medical bills on time. Reminds one of global warming stats. There were an estimated 18.1 million cancer cases around the world in 2020, according to theWorld Cancer Research Fund International. But why not also kick in for some prostate research? CT scan orMRI. health information, we will treat all of that information as protected health Take steps to: Some medications have been found to reduce the risk of precancerous polyps or colon cancer. Cholangioscopy. You will also The World Cancer Research Fund suggests that higher cancer rates are impacted by diet and lifestyle factors. Risk of gastrointestinal cancers in patients with cystic fibrosis: A systematic review and meta-analysis. Diagnosed with terminal lung cancer, Joe was told he had about 3 months to live. We're improving the lives of cancer patients and their families through advocacy, research, and patient support to ensure that everyone has an opportunity to prevent, detect, treat, and survive cancer. Making Strides Against Breast Cancer Walks, ACS Center for Diversity in Research Training, Things to Know About the Cost of Your Cancer Treatment, If You Have Problems Paying a Medical Bill, Programs and Resources to Help With Cancer-related Expenses, Social Security Disability Insurance for People with Cancer, Supplemental Security Income for People with Cancer. A cell's DNA contains a set of instructions that tell a cell what to do. If you have an increased risk of colon cancer, discuss your risk factors with your doctor to determine whether preventive medications are safe for you. Research shows that certain things can raise your chances of getting it, including long-term inflammation from conditions including: Primary sclerosing cholangitis. Elsevier; 2021. https://www.clinicalkey.com. "The . Some state radon offices offer kits for free. privacy practices. Cholangiocarcinoma (adult). You can take chemo by mouth or through a shot into a vein. National Association of Insurance Commissioners Learn more about the types, causes, risk factors, diagnosis, treatment, and . Cholangiocarcinoma (bile duct cancer) care at Mayo Clinic. I guess it has something to do with the diet and lifestyle. Recording cancer occurrences and deaths is a very complex task, says Timothy Rebbeck, PhD, associate director for Dana-Farbers Center for Cancer Equity and Engagement and researcher in the Division of Population Sciences. Genetic/familial high-risk assessment: Colorectal. To add EVEN MORE proof, Little Bill's best friend from school is a white boy with red hair, which is awfully similar to Caillou's best friend, Leo. In others, it may never go away entirely. This site complies with the HONcode standard for trustworthy health information: verify here. However, the study did not conclude that CIU causes cancer, and the myth has been debunked by numerous scientific organizations. Accessed May 28, 2021. How long was the time between diagnosis to surgery for you? I think that Little Bill and Caillou are both telling stories from the same life but through different perspectives. Rest will help, but so will some exercise. So it turns out, there's a very sweet and inspirational meaning behind Caillou being bald. My failure to proofread. Then-Speaker Curt Pringle (R-Garden Grove) denies it. Certain tests can find signs of bile duct cancer, including: Blood tests. Cancer is not one disease. Anderson CD. You can't see or smell radon, but a special test can check the levels in your home. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Mayo Clinic Q and A: Advances in screening for colon cancer, Science Saturday: Mayo Clinic patient grateful after genetic test leads to unexpected, early detection of colon cancer, Mayo Clinic study shows AI may improve prediction of colorectal cancer recurrence. Contact the American Cancer Society office at 1-800-227-2345 for more information on whether this program is available in your area. There is a problem with (If youre covered bymore than one plan, wait until you have the EOB from all of them.) Below are some of the resources we provide. information and will only use or disclose that information as set forth in our notice of Pete Wilson has proposed increasing that by $6.5 million in the next budget.. .st3 { . Do what you can to take care of your liver. Trucks, buses, trains, and even some cars run on diesel fuel. Vaginal discharge colored with blood. 2018;378:1177. Mayo Clinic is a not-for-profit organization. Breast cancer, for example is relatively identifiable, and doesnt cause immediate death. In 1994, then-Assemblyman Stan Statham (R-Chico) authored a bill that contained a 2-cent-per-pack cigarette tax increase to finance research. Your in-depth coping with cancer guide will be in your inbox shortly. You can contact your state insurance commission for insurance information specific to your state, or for problems you are having with your insurance plan, Patient Advocate Foundation (PAF) Rebbeck also says that the accuracy of cancer data can vary depending on the type of cancer. Rectal bleeding or blood in your stool. It's the No. AskMayoExpert. Together, were making a difference and you can, too. Leo's parents get divorced and Leo's mother is unable to take care of two children, thus, Caillou's family takes care of Rosie. .st1 { Tom Sizemores ex reveals harrowing final text actor sent before tragic death, Saving Private Ryan star Tom Sizemore dies aged 61 after suffering brain aneurysm, Teen Mom fans are convinced Kail's son leaked news of star's 'secret 5th baby', Kim Kardashian shows off her real hips and butt in unedited new pics, 2020 THE SUN, US, INC. ALL RIGHTS RESERVED | TERMS OF USE | PRIVACY | YOUR AD CHOICES | SITEMAP, The Little Couple's home in St Petersburg, FL, $2M for their waterfront mansion in Florida. American Cancer Society medical information is copyrightedmaterial. A single copy of these materials may be reprinted for noncommercial personal use only. ", North American Menopause Society: "Hormone Therapy: Benefits and Risks. Ask the doctor or facility if they can give you the same discounts that they give Medicare (or even major health insurance companies) so that you can pay the bill. But in the Assembly it was killed by the GOP-led Appropriations Committee. Jen Arnold, 46, is one half of The Little Couple, a reality show on the TLC network that she shares with husband Bill Klein, 45. There is a problem with Half the nations of the world dont even get people in to be diagnosed let alone treated. Those are thin tubes about 4 to 5 inches long that move a fluid called bile from your liver to your gallbladder and small intestine. Reddit and its partners use cookies and similar technologies to provide you with a better experience. For this reason, doctors recommend regular screening tests to help prevent colon cancer by identifying and removing polyps before they turn into cancer. Website:http://naic.org/state_web_map.htm, Offers contact information for your state insurance commission. Are they free? Cancer.Net. Exactly why is a mystery. And cancerous cells can travel to other parts of the body to form deposits there (metastasis). Most skin cancer cases are due to UV rays. Your doctor injects an inactive form of a certain medication into your vein. .st2 { Whether you or someone you love has cancer, knowing what to expect can help you cope. Your doctor uses medication to put you to sleep and then makes a small cut in your belly. The IDEA (International Duration Evaluation of Adjuvant Chemotherapy) collaboration: prospective combined analysis of phase III trials investigating duration of adjuvant therapy with the FOLFOX (FOLFOX4 or Modified FOLFOX6) or XELOX (3 versus 6 months) regimen for patients with stage III colon cancer: trial design and current status. Yes. There is no exact answer to this question as it is impossible to know definitively whether or not Caillou has cancer. The neonatologist went into remission back in 2014 after battling the disease for a year. clip-path: url(#SVGID_4_); What does it take to outsmart cancer? "I had . Journal of Surgical Oncology. aren't discussed as often. Review/update the https://www.uptodate.com/contents/search. If you notice any persistent symptoms that worry you, make an appointment with your doctor. This content does not have an English version. 1990;322:352. Your body should function better at repairing broken DNA and eliminating these alien cells, but as we age the repair processes of the body slowly break down. The conclusions drawn from this are specious at best. Those factors are big drivers of high cancer rates. While many of us are aware of the cancersand treatmentsthat cats and dogs undergo, cancers and treatment options in small animals (rabbits, ferrets, rodents, etc.) The wide discrepancy in rates of cancer between the countries with the highest rates and the lowest rates is most likely due to insufficient poor data collection in developing nations. Even if a woman has already been diagnosed with cancer, she may receive free treatment if she qualifies. Accessed April 6, 2021. In 2016, it's expected that more than 1.6 million new cases of cancer will be diagnosed in the United States. But basically it has been Republican men who have killed prostate research. Bill has a rare variation of a skeletal dysplasia called Spondyloepiphyseal Dysplasia (or SED) and has had more than 20 surgeries in his lifetime, while Jen stands at just 3' 2" and has a similar, and also rare, type of dwarfism called Spondyloepiphyseal Dysplasia Type Strudwick. } Energy . Colon cancer screening: At what age can you stop? Connect with others like you for support and answers to your questions in the Colorectal Cancer support group on Mayo Clinic Connect, a patient community. 2017;31:455. Theyll also check for masses, tenderness, or fluid buildup in your belly. Our Online Second Opinion program lets adult patients from all over the world receive expert second opinions from Dana-Farber oncologists without leaving home. Damage tissues and cells. He was fond of deer hunting which was common in our desert type villages. A cell's DNA contains the instructions that tell a cell what to do. Persistent abdominal discomfort, such as cramps, gas or pain. Some causes of liver disease can't be prevented, but others can. Nature Reviews Gastroenterology & Hepatology. Cancer Legal Resource Center(CLRC). Since these exposures are changing in Africa and other regions to look more like exposures in developed nations, we can guess that cancer rates in many parts of the world will increase in the coming years.. Kandel P, et al. but many. CEREAL GRAINS largely! We can also help you find other free or low-cost resources available. WebMD does not provide medical advice, diagnosis or treatment. Murdoch has survived scandal after scandal. For cancer patients in treatment or less than 2 years out of treatment, Cancer Legal Resource Center (CLRC) Unexplained weight loss. You've probably heard the word "carcinogen" pop . More than 90% of oral. Also inspiring are the professional demeanor of the people who interact with Little Bill and his family, the seamless sense of community, and the Afro-centric world in which these characters . Signs and symptoms of colon cancer include: A persistent change in your bowel habits, including diarrhea or constipation or a change in the consistency of your stool. Try to meet face-to-face with someone in the office, hospital, or clinic that sent you the bill. His friend also died due to blood cancer with same surroundings, he was also fond of deer hunting and eat the deer as my father, he died around +90, his all other organs were healthy no sugar no blood pressure, etc, my fathers 2nd friend also died due to blood cancer, he was also fond of deer hunting and eating deer meat, he died in young age around 50. 2013;9(3):261-269. Dont pay any bill until you have the final Explanation of Benefits (EOB) form from your insurance company. Xeloda for colon cancer - Scared about side effects and need support. Yellowing of your skin and the whites of your eyes (jaundice), Abdominal pain on the right side, just below the ribs. Even during cancer treatment, you can take steps to feel as healthy as possible. Mayo Clinic researchers study rare genetic condition to tackle colorectal cancer, Science Saturday: What you should know about genetics, colorectal cancer, AI reduces miss rate of precancerous polyps in colorectal cancer screening, Mayo Clinic Q&A podcast: Colorectal cancer on the rise in younger adults, Mayo Clinic Minute: What to know when colorectal cancer runs in the family, Mayo Clinic Minute: Breaking down colorectal cancer, Bowel cancer: Mayo Clinic Healthcare expert describes role hard-to-see polyps play in cancer risk, Tumor cell PD-L1 may mediate sensitivity to chemotherapy in colorectal cancer treatment, Mayo Clinic Minute: When colon cancer spreads to the liver, Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients, Mayo Clinic Q and A: Colorectal cancer screening remains important, Colorectal cancer cases rising in younger adults, screenings are down, Sharing Mayo Clinic: Celebrating 5 years cancer-free after colon cancer, Updated screening guidelines for colorectal cancer. Radiation. It is difficult to nail down exactly reasons for different rates among countries, or why Australia and the United States have higher rates versus Israel and Japan, for example. He preferred the University of California, which traditionally handles state-sponsored research. DOCTOR JENNIFER Arnold from the hit TLC series The Little Couple overcame a rare form of cancer years ago that hasn't returned since her remission. Last year, Watson obliged by excluding the private foundation and directing the Wilson administration to set up the program. Meals in Niger usually start with colorful salads made from seasonal vegetables. The two had been married 35 years. When you can, avoid idling in traffic or spending time next to diesel-run vehicles. Moertel CG, et al. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Is Caillou bald or does he have cancer? ", FDA: "Acrylamide: Information on Diet, Food Storage and Food Preparation. Ironically, the legislator who most frequently has been asking that question is a woman, Sen. Diane Watson (D-Los Angeles), who chairs the Senate Health and Human Services Committee. Lip cancer is the most common cancer of the mouth. information submitted for this request. This is a rare treatment that can sometimes cure bile duct cancer. Cholangiocarcinoma happens when cells in the bile ducts develop changes in their DNA. Review/update the National Comprehensive Cancer Network. From plywood to some fabrics, this chemical is used in many household products. Liver fluke infection. Asbestos. People whose cancers start outside the liver tend to do better than those who have tumors inside it. Cancer.org is provided courtesy of the Leo and Gloria Rosen family. National Cancer Institute. Seven times as much federal money was spent on breast cancer research as for prostate study; for AIDS, it was 20 times as much. In 1995, Watson took over the project. Accessed April 6, 2021. Colon cancer treatment (PDQ) Patient version. Your doctor takes a sample of bile duct cells or tissue, and a technician checks them under a microscope. She plans to fund it with $18 million. ", Cancer Council: "How ultraviolet (UV) radiation causes skin cancer. Also, other Republicans note, the GOP basically thinks disease research is a federal responsibility. Maintain a healthy weight. This content does not have an English version. Pollution and climate change make these rays stronger. A carcinogen is something that can cause you to have cancer. Are there other methods to pay my bill? privacy practices. Accessed Jan. 30, 2019. Some of the agencies that advertise themselves as non-profits have hidden fees that can add to your debt. North Little Rock, AR 72190-4280. Hepatobiliary cancers. An MRI uses high-powered magnets to show organs and other things inside your body. During this time, Caillou has become closer to his classmates, and became Dora's new girlfriend. Although we will soon cure many forms of cancer with new viral treatment modalities, it is important to remember that we all suffer from the same genetic disease: physical aging. We can conquer the disease of aging as well as all cancers. This is called, The distal region, where your common bile duct passes through your. 2005; doi:10.1097/01.sla.0000179678.13285.fa. For instance, some evidence links a reduced risk of polyps and colon cancer to regular use of aspirin or aspirin-like drugs. Husband Bill is an entrepreneur and a small business owner. to pneall@gmail.com. Duration of adjuvant chemotherapy for stage III colon cancer. Now lets cure aging. Some of the issue arises from the data that can be collected, says Rebbeck. Cholangiocarcinoma, also known as bile duct cancer, occurs mostly in people older than age 50, though it can occur at any age. Try to meet face-to-face with someone in the office, hospital, or clinic that sent you the bill. To provide you with the most relevant and helpful information, and understand which But the Assembly GOP objected to raising the tax again and the bill died. It activates the drug, killing the cancer cells. The show is set in an urban Utopia, which isn't a bad place for young viewers to visit. Plymouth Meeting, Pa.: National Comprehensive Cancer Network. TTY: 1-800-829-4059 In some cases, high rates of certain types of cancer are also tied up in the lack of preventative measures. Laparoscopy. If it's part of your job, follow workplace safety guidelines to protect your health. Toll-free number: 1-866-843-2572 (may need to leave a number for a call back) More than 40% of people over 50 have precancerous polyps in the colon, according to the American Society for Gastrointestinal Endoscopy. Thiels CA, et al. The program has been providing breast and cervical cancer screenings to the women of Illinois since 1995. Website:www.irs.gov, Has answers to tax questions, tax forms, and referrals to free tax help for those who qualify. The couple paid $2M for their waterfront mansion in Florida where they've been quarantining amid the coronavirus pandemic. This has led to higher rates of lung cancer in northern Africa. You can cut the amount you eat by baking, roasting, frying, and toasting foods until they're a tan color instead of golden or deep brown.Acrylamide is also found in many products you buy as well as in tobacco smoke. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Assortment of Health Products from Mayo Clinic Store, Assortment of Ostomy Supplies at Mayo Clinic Store, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter Digital Edition. They'd been living in an apartment while their house was being made accessible and modernized.Aug 11, 2022 Advertisement Advertisement Bloody, dark or . 2017; doi:10.1371/journal.pone.0186643. Medically Reviewed by Jennifer Robinson, MD on August 11, 2022. Polyps may be small and produce few, if any, symptoms. The show has been on the air for 11 years and follows the lives of the couple and their children, Will, 10, and Zoe, 8 whom they adopted from China and India as toddlers. Start by cutting down on alcohol and quitting tobacco. On June 8, Medley lost his wife, Paula, after a five-year battle with Parkinson's disease. This explains why Little Bill has no little sister. A persistent change in your bowel habits, including diarrhea or constipation or a change in the consistency of your stool, Persistent abdominal discomfort, such as cramps, gas or pain, A feeling that your bowel doesn't empty completely. Most of our efforts should go into halting and reversing that disease, whether based on the free radical theoru or the neuro endocrine theory or other models. American Cancer Society: "Known and Probable Human Carcinogens," "Harmful Chemicals in Tobacco Products," "Diesel Exhaust and Cancer," "How to Test Your Home for Radon," "Asbestos and Cancer Risk," "World Health Organization Says Processed Meat Causes Cancer," "Talcum Powder and Cancer," "Does UV Radiation Cause Cancer?" If we combine this information with your protected Signs and symptoms of colon cancer include: Many people with colon cancer experience no symptoms in the early stages of the disease. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Sign up for free and receive the latest on colon cancer treatment, care and management. Your chance of getting sick depends on many things. Countries like Niger and Sudan do not necessarily have lower rates of cancer; rather, these nations simply do not have the infrastructure to accurately and completely identify and register those cases. Over all, the site bristled with brain-cancer warnings. Around one-third of deaths from cancer are due to tobacco use, high body mass index, alcohol consumption, low fruit and vegetable intake, and . ", Environmental Protection Agency: "Health Risk of Radon," "How do I get a radon test kit? 4. Make a donation. You will receive the first colon cancer care journey message in your inbox shortly, which will include the latest treatment options, innovations and other information from our colon cancer experts. This is a myth that originated from a misreading of a study that found a link between CIU and a rare form of cancer called adenocarcinoma. Even light smoking raises your risk, so talk to your doctor about ways to quit. Grothey A, et al. When symptoms appear, they'll likely vary, depending on the cancer's size and location in your large intestine. You will probably have to be persistent about this. We were fine with the bill, says Jeanne Cain, the governors legislative lobbyist. Photodynamic therapy. There isn't enough evidence to recommend these medications to people who have an average risk of colon cancer. and it doesn't have to do with cancer or any other sickness. Trained volunteers drive patients and families to hospitals and clinics for treatment. It's held in the gallbladder until needed to help digest food. Accessed athttps://www.healthcare.gov/appeal-insurance-company-decision/appeals/ on May 3, 2019. How much you've been exposed to it is part of it. Your bile duct is deep inside your body, so unlike with some other cancers, you wont see or feel problems in the early stages. You may occasionally receive promotional content from the Los Angeles Times. A CT scan is a powerful X-ray that makes detailed pictures inside your body. Accessed. If Your Health Insurance Claim Is Denied. Here are some other figures: Last year, 317,000 American men learned they had prostate cancer, compared with 184,000 new cases of breast cancer and 72,000 cases of AIDS. They then take X-rays to look for tumors. Accessed Jan. 14, 2021. Talk about your options with your doctor, and together you can decide which tests are appropriate for you. But Wilson vetoed it, apparently because of some turf obsession. State taxpayers also are spending $92 million on AIDS programs and Wilson is asking for another $17 million. Cancer often causes fatigue, or extreme tiredness. Dean PA, et al. Think about it, both of them are bald, which is rare for kids their age. Warner KJ. For some other sources of help with expenses, see Programs and Resources to Help with Cancer-related Expenses.. Liver transplant. The state now is spending $34 million annually on breast cancer programs--including $17 million for research--and Gov. Choledochal cysts. Accessed athttps://thedrlc.org/cancer/publications-webinars/financial-publications/ on April 19, 2019. This year hes a principal coauthor. We couldnt do what we do without our volunteers and donors. A smart, inquisitive five year old boy called "Little Bill" explores what life is like with the help of his big imagination. Patient Advocate Foundation (PAF).